GLC1F, a new primary open-angle glaucoma locus, maps to 7q35-q36
MK Wirtz, JR Samples, K Rust, J Lie… - Archives of …, 1999 - jamanetwork.com
Background A large family with adult-onset primary open-angle glaucoma (POAG) was
identified. Objective To initiate a genome-wide scan to map thePOAGlocus in this family.
Methods Blood samples or buccal swabs were obtained from 25 members of a large family
with POAG after informed consent was obtained. Members and their spouses were
evaluated clinically for POAG on the basis of intraocular pressures, cupping of discs, and
visual fields. DNA samples were used for a genome-wide screen using microsatellite …
identified. Objective To initiate a genome-wide scan to map thePOAGlocus in this family.
Methods Blood samples or buccal swabs were obtained from 25 members of a large family
with POAG after informed consent was obtained. Members and their spouses were
evaluated clinically for POAG on the basis of intraocular pressures, cupping of discs, and
visual fields. DNA samples were used for a genome-wide screen using microsatellite …