Glaucoma is a disease in which retinal ganglion cells (RGCs) die leading ultimately to
blindness. Over the past decade and a half, information has begun to emerge regarding
specific molecular responses of the retina to conditions of elevated intraocular pressure
(IOP). It is now clear that the state of the RGC in glaucoma depends on a balance of pro-
survival and pro-death pathways in the retina and details of these responses are still being
worked out. In this review, we will discuss the evidence supporting the involvement of …