The effects of starvation and refeeding on carbohydrate and lipid metabolism in vivo and in the perfused rat liver: the RELATIONSHIP between FATTY ACID …

JD McGarry, JM Meier, DW Foster - Journal of Biological Chemistry, 1973 - ASBMB
The time course of changes in a variety of physiological parameters concerned with
carbohydrate and lipid metabolism has been studied both in vivo and in the isolated
perfused liver during induction and reversal of starvation ketosis in the rat. The data
obtained demonstrate that surprisingly brief periods of starvation and refeeding exert
dramatic effects on glucose and fatty acid metabolism in the intact animal and that generally
synchronous changes occur in the ketogenic and gluconeogenic capacities of the perfused …