Improvement in peripheral glucose uptake after gastric bypass surgery is observed only after substantial weight loss has occurred and correlates with the magnitude of …

GM Campos, C Rabl, S Peeva, R Ciovica… - Journal of …, 2010 - Elsevier
Introduction Altered gut and pancreatic hormone secretion may bolster resolution of insulin
resistance after Roux-en-Y gastric bypass (RYGB), but the independent effects of weight
loss and hormonal secretion on peripheral glucose disposal are unknown. Methods Two
groups of nondiabetic morbidly obese patients were studied: RYGB followed by
standardized caloric restriction (RYGB, n= 12) or caloric restriction alone (diet, n= 10).
Metabolic evaluations (euglycemic–hyperinsulinemic clamp, meal tolerance test) were done …