Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment
JL Bayer-Carter, PS Green, TJ Montine… - Archives of …, 2011 - jamanetwork.com
Objective To compare the effects of a 4-week high–saturated fat/high–glycemic index (HIGH)
diet with a low–saturated fat/low–glycemic index (LOW) diet on insulin and lipid metabolism,
cerebrospinal fluid (CSF) markers of Alzheimer disease, and cognition for healthy adults and
adults with amnestic mild cognitive impairment (aMCI). Design Randomized controlled trial.
Setting Veterans Affairs Medical Center clinical research unit. Participants Forty-nine older
adults (20 healthy adults with a mean [SD] age of 69.3 [7.4] years and 29 adults with aMCI …
diet with a low–saturated fat/low–glycemic index (LOW) diet on insulin and lipid metabolism,
cerebrospinal fluid (CSF) markers of Alzheimer disease, and cognition for healthy adults and
adults with amnestic mild cognitive impairment (aMCI). Design Randomized controlled trial.
Setting Veterans Affairs Medical Center clinical research unit. Participants Forty-nine older
adults (20 healthy adults with a mean [SD] age of 69.3 [7.4] years and 29 adults with aMCI …
