Neural stem cells and the origin of gliomas
N Sanai, A Alvarez-Buylla… - New England Journal of …, 2005 - Mass Medical Soc
N Sanai, A Alvarez-Buylla, MS Berger
New England Journal of Medicine, 2005•Mass Medical SocLittle progress has been made in the treatment of gliomas during the past 25 years. One
reason is our poor understanding of the cell of origin in these tumors and of the mechanisms
that bring that cell into a malignant state. This review argues that gliomas arise from neural
stem cells and discusses the clinical implications of this concept.
reason is our poor understanding of the cell of origin in these tumors and of the mechanisms
that bring that cell into a malignant state. This review argues that gliomas arise from neural
stem cells and discusses the clinical implications of this concept.
Little progress has been made in the treatment of gliomas during the past 25 years. One reason is our poor understanding of the cell of origin in these tumors and of the mechanisms that bring that cell into a malignant state. This review argues that gliomas arise from neural stem cells and discusses the clinical implications of this concept.
The New England Journal Of Medicine