B-cell–activating factor levels are associated with antibody-mediated histological damage in kidney transplantation

C Sango, D Merino, D San Segundo, E Rodrigo… - Transplantation …, 2016 - Elsevier
Introduction Along with death engraftment, in recent years, antibody-mediated damage has
been identified as the leading cause of loss of kidney transplants. Despite the recognition of
the role of the B-lymphocyte subpopulation in the development of both tolerance and
rejection, little is known about the trigger mechanisms and effectors of this humoral
response. Background We analyzed the relationship between B lymphocyte subpopulations
and levels of B-cell–activating factor (BAFF) with the histological findings in biopsies of renal …