[HTML][HTML] De novo donor HLA-specific antibodies after heart transplantation are an independent predictor of poor patient survival

JD Smith, NR Banner, IM Hamour, M Ozawa… - American journal of …, 2011 - Elsevier
Preformed donor HLA-specific antibodies are a known indicator for poor patient survival
after cardiac transplantation. The role of de novo donor-specific antibodies (DSA) formed
after cardiac transplantation is less clear. Here we have retrospectively analyzed 243
cardiac transplant recipients, measuring HLA antibody production every year after
transplantation up to 13 years post-transplant. Production of de novo DSA was analyzed in
patients who had been negative for DSA prior to their transplant. DSA including transient …