[HTML][HTML] Cold induces reactive oxygen species production and activation of the NF‐kappa B response in endothelial cells and inflammation in vivo
EM Awad, SY Khan, B Sokolikova, PM Brunner… - Journal of Thrombosis …, 2013 - Elsevier
Background Organs intended for transplantation are generally stored in the cold for better
preservation of their function. However, following transplantation and reperfusion, the
microvasculature of transplanted organs often proves to be activated. Extensive leukocyte
adhesion and microthrombus formation contribute to failure of the transplanted organ.
Objectives In this study we analyzed cold‐induced changes to the activation status of
cultured endothelial cells, possibly contributing to organ failure. Methods We exposed …
preservation of their function. However, following transplantation and reperfusion, the
microvasculature of transplanted organs often proves to be activated. Extensive leukocyte
adhesion and microthrombus formation contribute to failure of the transplanted organ.
Objectives In this study we analyzed cold‐induced changes to the activation status of
cultured endothelial cells, possibly contributing to organ failure. Methods We exposed …