[PDF][PDF] A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection
Cell, 2020•cell.com
SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from
silent infection to lethal disease. The role of human genetics in determining clinical response
to the virus remains unclear. Studies of outliers—individuals remaining uninfected despite
viral exposure and healthy young patients with life-threatening disease—present a unique
opportunity to reveal human genetic determinants of infection and disease.
silent infection to lethal disease. The role of human genetics in determining clinical response
to the virus remains unclear. Studies of outliers—individuals remaining uninfected despite
viral exposure and healthy young patients with life-threatening disease—present a unique
opportunity to reveal human genetic determinants of infection and disease.
SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers—individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease—present a unique opportunity to reveal human genetic determinants of infection and disease.
cell.com