[HTML][HTML] Treg cells: a potential regulator for IL-22 expression?

S Lin, X Yang, D Liang, SG Zheng - International journal of clinical …, 2014 - ncbi.nlm.nih.gov
S Lin, X Yang, D Liang, SG Zheng
International journal of clinical and experimental pathology, 2014ncbi.nlm.nih.gov
Abstract Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by
innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated
that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are
important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22
expression. In the review, we discuss the updated advancement on Tregs function and its
regulatory role on IL-22 expression.
Abstract
Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.
ncbi.nlm.nih.gov