Pulmonary arterial lesions in explanted lungs after transplantation correlate with severity of pulmonary hypertension in chronic obstructive pulmonary disease
J Carlsen, KH Andersen, S Boesgaard… - The Journal of Heart and …, 2013 - Elsevier
BACKGROUND: Pulmonary vascular findings are largely unreported in end-stage chronic
obstructive pulmonary disease (COPD). METHODS: Pulmonary vascular lesions in
explanted lungs from 70 patients with COPD/emphysema or α-1-antitrypsin deficiency were
analyzed retrospectively. Patients were stratified by the presence and severity of pulmonary
hypertension (PH) assessed by right-heart catheterization in 3 hemodynamically distinct
groups:(1) non-PH (mean pulmonary arterial pressure [mPAP]< 25 mm Hg),(2) mild to …
obstructive pulmonary disease (COPD). METHODS: Pulmonary vascular lesions in
explanted lungs from 70 patients with COPD/emphysema or α-1-antitrypsin deficiency were
analyzed retrospectively. Patients were stratified by the presence and severity of pulmonary
hypertension (PH) assessed by right-heart catheterization in 3 hemodynamically distinct
groups:(1) non-PH (mean pulmonary arterial pressure [mPAP]< 25 mm Hg),(2) mild to …