Systemic inflammation in patients with COPD and pulmonary hypertension

P Joppa, D Petrasova, B Stancak, R Tkacova - Chest, 2006 - Elsevier
Study objectives COPD is a systemic disorder that is associated with increases of
inflammatory proteins in systemic circulation. However, no data on the potential role of
systemic inflammation in pulmonary hypertension secondary to COPD are available.
Therefore, our aim was to investigate the degree of systemic inflammation reflected by
circulatory levels of C-reactive protein (CRP), tumor-necrosis factor (TNF)-α, and interleukin
(IL)-6 in COPD patients with and without pulmonary hypertension. Design Cross-sectional …