Iloprost improves gas exchange in patients with pulmonary hypertension and ARDS
E Sawheny, AL Ellis, GT Kinasewitz - Chest, 2013 - Elsevier
Objective We hypothesized that nebulized iloprost would improve ventilation-perfusion
matching in patients with pulmonary hypertension and ARDS as reflected by an improved
Pa o 2/F io 2 ratio and Pa o 2 without adversely affecting lung mechanics or systemic
hemodynamics. Methods Patients with ARDS and pulmonary hypertension were enrolled.
With constant ventilator settings, hemodynamics, airway pressures, and gas exchange
measured at baseline were compared with values 30 min after administration of 10 μg …
matching in patients with pulmonary hypertension and ARDS as reflected by an improved
Pa o 2/F io 2 ratio and Pa o 2 without adversely affecting lung mechanics or systemic
hemodynamics. Methods Patients with ARDS and pulmonary hypertension were enrolled.
With constant ventilator settings, hemodynamics, airway pressures, and gas exchange
measured at baseline were compared with values 30 min after administration of 10 μg …