Steroids in idiopathic pulmonary fibrosis: a prospective assessment of adverse reactions, response to therapy, and survival
KR Flaherty, GB Toews, JP Lynch III… - The American journal of …, 2001 - Elsevier
PURPOSE: We evaluated the risk and potential benefit of high-dose corticosteroid therapy in
patients with idiopathic pulmonary fibrosis. SUBJECTS AND METHODS: We prospectively
studied 41 patients with previously untreated, biopsy-proven idiopathic pulmonary fibrosis.
Before treatment, we calculated clinical, radiographic, and physiologic severity-of-illness
scores for each patient. We scored high-resolution computerized tomographic (CT) scans for
ground glass and interstitial opacity. We determined the extent of cellular infiltration …
patients with idiopathic pulmonary fibrosis. SUBJECTS AND METHODS: We prospectively
studied 41 patients with previously untreated, biopsy-proven idiopathic pulmonary fibrosis.
Before treatment, we calculated clinical, radiographic, and physiologic severity-of-illness
scores for each patient. We scored high-resolution computerized tomographic (CT) scans for
ground glass and interstitial opacity. We determined the extent of cellular infiltration …