Colchicine, D-penicillamine, and prednisone in the treatment of idiopathic pulmonary fibrosis: a controlled clinical trial

M Selman, G Carrillo, J Salas, RP Padilla… - Chest, 1998 - Elsevier
Study objective We compared the long-term efficacy of the combination of colchicine and/or
D-penicillamine with prednisone, in comparison to prednisone alone in patients with
idiopathic pulmonary fibrosis (IPF). Design Nonrandomized prospective study in patients
with IPF confirmed by biopsy specimen. Setting National Institute of Respiratory Diseases,
Mexico. Patients Fifty-six IPF patients were included in this study. Patients received either
colchicine/prednisone (n= 19), D-penicillamine/prednisone (n= 11), D-penicillamine …