[HTML][HTML] Efficacy of FP‐025: A novel matrix metalloproteinase‐12 (MMP‐12) inhibitor in murine allergic asthma
L Ravanetti, T Dekker, L Guo, A Dijkhuis, BS Dierdorp… - Allergy, 2023 - ncbi.nlm.nih.gov
L Ravanetti, T Dekker, L Guo, A Dijkhuis, BS Dierdorp, Z Diamant, S Florquin, R Lutter
Allergy, 2023•ncbi.nlm.nih.govFIGURE 1 FP-025 significantlysuppressedallergicasthmafeatu….(A) Experimentaloutline
(Appendix S1).(B) The body weight assesseddailyduringFP-025 treatment.(C) AnalysisoftheAHRonday36ofthesensitizatio…
.(D) Totalcellcounts,(E) differential immune cell count in BAL. Data are representative of two
independent experiments with four mice per group.(C) Data represent mean±SEM (two-
wayANOVAfollowedbyBonferroni'spost-test);* p< 0.05,** p< 0.01,*** p< 0.001
forthecomparisonbetweenindicated groups.(D, E) Datarepresentmean±SEM (t-test);* p< …
(Appendix S1).(B) The body weight assesseddailyduringFP-025 treatment.(C) AnalysisoftheAHRonday36ofthesensitizatio…
.(D) Totalcellcounts,(E) differential immune cell count in BAL. Data are representative of two
independent experiments with four mice per group.(C) Data represent mean±SEM (two-
wayANOVAfollowedbyBonferroni'spost-test);* p< 0.05,** p< 0.01,*** p< 0.001
forthecomparisonbetweenindicated groups.(D, E) Datarepresentmean±SEM (t-test);* p< …
FIGURE 1 FP-025 significantlysuppressedallergicasthmafeatures.(A) Experimentaloutline (Appendix S1).(B) The body weight assesseddailyduringFP-025 treatment.(C) AnalysisoftheAHRonday36ofthesensitizationschedulebyPenh.(D) Totalcellcounts,(E) differential immune cell count in BAL. Data are representative of two independent experiments with four mice per group.(C) Data represent mean±SEM (two-wayANOVAfollowedbyBonferroni'spost-test);* p< 0.05,** p< 0.01,*** p< 0.001 forthecomparisonbetweenindicated groups.(D, E) Datarepresentmean±SEM (t-test);* p< 0.05,** p< 0.01,*** p< 0.001 forthecomparisonbetweenindicatedgroups.
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