The importance of proper skin wound healing becomes evident when our body's repair
mechanisms fail, leading to either non-healing (chronic) wounds or excessive repair
(fibrosis). Chronic wounds are a tremendous burden for patients and global healthcare
systems and are on the rise due to their increasing incidence with age and diabetes.
Curiously, these same risk factors also sign responsible for the development of hypertrophic
scarring and organ fibrosis. Activated repair cells–myofibroblasts–are the main producers …