Background The clinical manifestations of bronchial remodeling in asthma and the potential
impact of this process on lung function remain unclear. We aimed to determine whether the
presence of pathologic features of airway remodeling in patients with asthma was
associated with steroid responsiveness in the short term. Methods Sixty-three consecutive
patients with severe asthma with chronic airflow impairment (post-bronchodilator FEV 1<
80% predicted values) were recruited, clinically characterized, and had an initial …