Venous engorged tissue flaps treated with medicinal leeches

IR Rodgers, AS Grove Jr… - Ophthalmic Plastic & …, 1992 - journals.lww.com
IR Rodgers, AS Grove Jr, DG Silverman
Ophthalmic Plastic & Reconstructive Surgery, 1992journals.lww.com
We evaluated the ability of leeches to improve the tolerance of pedicle flaps to periods of
venous congestion. Axial pedicle flaps were created on 14 rabbit ears; the venous
circulation of each flap was compromised with a suture ligature. Medicinal leeches were
applied to seven flaps; the other seven flaps were untreated. Tissue viability was assessed
by both clinical examination and fluorometric analysis of fluorescein dye delivery. Leech-
treated flaps showed poorer reperfusion than untreated flaps. No statistically significant …
Abstract
We evaluated the ability of leeches to improve the tolerance of pedicle flaps to periods of venous congestion. Axial pedicle flaps were created on 14 rabbit ears; the venous circulation of each flap was compromised with a suture ligature. Medicinal leeches were applied to seven flaps; the other seven flaps were untreated. Tissue viability was assessed by both clinical examination and fluorometric analysis of fluorescein dye delivery. Leech-treated flaps showed poorer reperfusion than untreated flaps. No statistically significant difference was found in comparing the two groups.
Lippincott Williams & Wilkins