Standard definitions and common data elements for clinical trials in patients with alcoholic hepatitis: recommendation from the NIAAA alcoholic hepatitis consortia
DW Crabb, R Bataller, NP Chalasani… - …, 2016 - gastrojournal.org
Alcohol-related steatosis is the most common manifestation of heavy drinking. A “standard
drink” in the United States (12 oz of beer, 5 oz of wine, or 1 oz of liquor) contains 14 g of
alcohol; volunteers drinking approximately 10 drinks per day for 2-3 weeks consistently
developed steatosis. 1 This level of drinking, often for decades, is observed in AH, 2, 3 but
only a minority of such drinkers develop AH. The best established risk factors are female sex
and increased body mass index; these and other factors have mainly been studied in the …
drink” in the United States (12 oz of beer, 5 oz of wine, or 1 oz of liquor) contains 14 g of
alcohol; volunteers drinking approximately 10 drinks per day for 2-3 weeks consistently
developed steatosis. 1 This level of drinking, often for decades, is observed in AH, 2, 3 but
only a minority of such drinkers develop AH. The best established risk factors are female sex
and increased body mass index; these and other factors have mainly been studied in the …