Research advances in ethanol metabolism

VA Ramchandani, WF Bosron, TK Li - Pathologie Biologie, 2001 - Elsevier
The pharmacokinetics of alcohol determines the time course of alcohol concentration in
blood after the ingestion of an alcoholic beverage and the degree of exposure of organs to
its effects. The interplay between the kinetics of absorption, distribution and elimination is
thus important in determining the pharmacodynamic responses to alcohol. There is a large
degree of variability in alcohol absorption, distribution and metabolism, as a result of both
genetic and environmental factors. The between-individual variation in alcohol metabolic …