Kawasaki disease: a brief history

JC Burns, HI Kushner, JF Bastian, H Shike… - …, 2000 - publications.aap.org
Tomisaku Kawasaki published the first English-language report of 50 patients with Kawasaki
disease (KD) in 1974. Since that time, KD has become the leading cause of acquired heart
disease among children in North America and Japan. Although an infectious agent is
suspected, the cause remains unknown. However, significant progress has been made
toward understanding the natural history of the disease and therapeutic interventions have
been developed that halt the immune-mediated destruction of the arterial wall. We present a …